Clone Number: 53,8
Immunogen: Recombinant Mouse talin-2 (aa2300-2542).
Concentration: IgG 1 mg/ml
Format: Purified
Storage buffer: PBS with <0.1% sodium azide
Additional info: Mouse anti Human Talin-2 antibody, clone 53.8 (also designated 121A) recognizes Talin-2, a high molecular weight skeletal protein involved in focal adhesion plaques. It plays a role in linking integrin to the actin cytoskeleton. It interacts with phosphatidylinositol-4-phosphate 5-kinase type I gamma (PIP5K1C), inducing its kinase activity. Mouse anti Human Talin-2 antibody, clone 53.8 recognizes an epitope within the range of ammino acids 2470-2500.
References: Liu J et al. PNAS 2015; 112: E4864-73/Prince HE & Yeh C. J Clin Lab Anal 2013; 27: 27-30/Qi L et al. J Cell Sci 2016; 129: 3661-74