Clone Number: AMY82
Immunogen: Prokaryotic recombinant protein corresponding to 134 amino acids of the human inhibin alpha molecule.
Concentration: Greater than or equal to 214 mg/L
Storage buffer: Tissue culture supernatant with 15mM Sodium azide
Additional info: Inhibins and activins are members of the transforming growth factor beta (TGFβ) family of cytokines. Inhibins are heterodimers consisting of a common α-subunit linked to either a βA subunit ( α-βA, forming inhibin A) or a βB subunit ( α-βB, forming inhibin B). Activins share the β-subunit with the inhibins and may be homo or heterodimers of β-subunits forming activin A (βA-βA), activin AB (βA-βB) or activin B (βB-βB). The expression of the α-subunit, and therefore of inhibins appears to be more restricted than that of the β-subunit, and therefore of activins. Inhibins and activins play a role in the regulation of pituitary follicle stimulating hormone (FSH) secretion.
References: Robertson D et al. Endocrine-Related Cancer. 2004; 11:35–49/Bernard J et al. Recent Progress in Hormone Research. 2001; 56:417–450
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