Clone Number: EBS-IF-003
Immunogen: cytoskeleton preparation from HeLa cells
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBS-IF-003 reacts with 53kDa (CK13) and 56.6kDa (CK10) cytokeratin proteins as indicated by immunoblotting. On formalin-fixed, paraffin-embedded tissue sections EBS-IF-003 recognizes only CK13. On cryostat sections EBS-IF-003 serves as differentiation-related marker of all stratified epithelia; it stains all suprabasal cells in both cornifying and noncornifying stratified epithelia and more differentiated cells of squamous carcinomas. In paraffin sections EBS-IF-003 does not stain CK10 positive, CK13 negative epithelia, as for example epidermis.
References: Ivanyi D. et al, J. Pathol. 159: 7-12 (1989)/Ivanyi D. et al, Am. J. Vet. Res. 53: 304-314 (1992)/Ivanyi D. et al, Am. J. Vet. Res. 54: 1095-1102 (1993)
English
Deutsch
