Clone Number: EBS-IF-001
Immunogen: cytokeratin-enriched extract of feline tongue epithelium
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBS-IF-001 Does not react with keratin polypeptides in immunoblotting. The specificity for keratin was established on the basis of antibody reactivity with intracytoplasmic intermediate filaments in epithelial, vimentin negative, human and feline cells. Distribution of the epitope strongly suggests that EBS-IF-001 reacts with keratins 5 and 14, most probably with a heterotypic complex formed by these keratins. EBS-IF-001 reacts positively with basal cells of all stratified epithelia, with myoepithelial cells and with most squamous cell carcinomas. It is useful in immunohistochemistry for typing of basal cells.
References: Ivanyi et al. Am. J. Vet. Res. 53: 304-314 (1992)/Balm A.J.M., Eur. Arch. Otorhinolaryngol. 253: 227-233 (1996)