Clone Number: RCK102
Immunogen: Lung cancer cell preparation
Concentration: n/a
Storage buffer: Hybridoma cell culture supernatant containing 0.09% sodium azide
Additional info: Mab RCK 102, directed against the 58 kD and 52.2 kD keratin proteins (keratins K5 and K8; formerly also designated cytokeratins 5 and 8 in the Moll catalogue of keratins), reacts with all epithelial cell types. No reaction is observed in non-epithelial tissues. The antibody can be used for the discrimination of carcinomas from non-epithelial tumors such as lymphomas, sarcomas and neural tumors. RCK 102 is applicable on frozen and paraffin-embedded tissue. Formalin fixation may cause antigen denaturation or masking. Therefore, protease digestion is necessary prior to antibody application.Positive control: Skin, cervix.
References: Broers, J.L.V., et al., 1986, J. cell Science 83, 37-60.