Clone Number: Lamb14
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: The antibody detects surface immunoglobulin on normal and neoplastic B-cells. Anti-lambda staining isseen in B-cell follicles of human lymphoid tissue. When dealing with B-cell neoplasms, thedetermination of light chain ratios remains helpful. Most B-cell lymphomas express either kappa orlambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positivecells. If only a single light chain type is detected, a lymphoproliferative disorder is very likely.
References: Hertel, BF, et al. Lab Invest 1977;36:12/Taylor, CL Arch Pathol Lab Med 1978;12:113-121/Abbondanzo SL et al. Ann Diagn Pathol. 1999 Oct;3(6):394
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