Clone Number: IPO-M6
Immunogen: human cell line HL-60
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: IPO-M6 reacts with human leukemia cell line HL-60 and immuno-precipitates two proteins with MW of 48 and 52 kDa. IPO-M6 does not stain B cell lines Daudy, PHS, Namalwa, RPMI-1788 and T-cell lines CCRF-HSB2, Jurkat and Molt-4. IPO-M6 can be applied for staining of monocytes and up to 10 % of lymphocytes from peripheral blood ofhealthy donors. Blast cells of patients with AMMonL (M5 following FAB classification), AMMonL (M4) and hairycells leukemia are IPO-M6 positive. The antigen, defined by IPO-M6, is particularly expressed on blood cellsfrom patients with infectious mononucleosis and CLL. Histiocytes and macrophages are also positive. Malignant cells frompatients with AML (M1 and M2), T-ALL, B ALL are IPO-M6 negative.
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