Clone Number: A103
Immunogen: Prokaryotic recombinant fusion protein corresponding to the human melan A molecule.
Concentration: Greater than or equal to 22 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.
References: Shidham VB et al. BioMed Central cancer. 2003; 3(1):15/Clarkson KS et al. Journal of Clinical Pathology. 2001; 54:196–200/De Vries TJ et al. Journal of Pathology. 2001; 193:13–20
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