Mouse anti-MHC I B27, clone EP-4 (Monoclonal)

Clone Number: EP-4

Immunogen: lymphocytes from an HLA-B27 patient

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: EP-4 recognizes the HLA-B27 cell surface antigen on human cells. HLA-B27 has been found to be highly associated (60%) with ankylosing spondylitis (Bekhterev's disease, MarieStrümpell disease or "bamboo spine"). While rheumatoid factor tests will be negative, testing for the presence of HLA-B27 in a patient can confirm the diagnosis of ankylosing spondylitis. Also postgonococcal arthritis and acute anterior uveitis are associated with HLA-B27.

References: Hansen JA et al. Hematol Oncol Clin North Am, 4(3): 507-515 (1990)/El-Shabrawi, Y. et al. Ophthalmology 113: 695-700 (2006)/Kellner H, Clin Investig. 72(4): 321-8 (1994)

• SKU: SANMON9868
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9868
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotype: IgM-k
• Host: Mouse