Clone: 10C4.
Background: The immunogen for the anti- mouse bcl - 2 was a synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence. Bcl-2 expression is associated with cell survival. The ratio of bcl-2 to other bcl-2 family members is believed to modulate apoptosis.
Purification Method: Protein A/G Chromatography.
Source: Mice were immunized with a synthetic peptide corresponding to amino acids 61 to 76 of the mouse bcl-2 sequence.
References: 1) D.Vaux et. al. (1988), 355: 440-442
2) D.Hockenberry et. al. (1990) Nature, 348:334-336
3) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834
4) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672.
UniProt: P10415 (Human)
P49950 (Rat).
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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