Clone Number: M3II-21
Immunogen: MRP3 aa 830-949
Concentration: 250 ug/ ml
Storage buffer: supernatant with 0.7% BSA and 0.1% sodium azide
Additional info: The antibody reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-21 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-21 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products. M3II-21 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples.
References: Kool et al. Cancer Res 1997; 57: 3537-3547/Kool et al. Proc Natl Acas Sci 1999; 96: 6915-9