Clone Number: BM-3
Immunogen: nuclei from Pokeweed mitrogen stimulated human peripheral blood lymphocytes
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: Induction studies using HL-60 cells showed that BM-3 identifies a nuclear antigen which is expressed during the early phases of myeloid differentiation, making BM-3 an early marker of myeloid differentiation. It is found in 98% of human granulocytes, in 80% of human monocytes and in myeloid precursor cells, residing in lymphoid and non-lymphoid tissues. It also reacts with a subset of myeloid leukemia cells. BM-3 has no reactivity with any other cell type in human tissues. In experiments using S-35 methionine labeled human myeloid leukemia cells BM-3 immunoprecipitated a 13 kDa protein.
References: Epstein, AL et al. Blood 70:1124-1130 (1987)/Murao et al, Cancer Research 45: 791-795 (1985)
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