Clone Number: Y85
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: The antibody reacts with progesterone receptor forms alpha and beta. This antibody stains nuclei inbreast, ovarian and endometrial epithelia, as well as myometrial nuclei. Since the early 1990’s theimmunohistochemical (IHC) assay determination of progesterone receptor status has replaced thedextran-coated charcoal method as a prognostic indicator in breast carcinoma. IHC has shown to besuperior in prognostic significance when using any one of several available methods of quantitationusing this technique.
References: Dabbs D. Diagnostic Immunohistochemistry, 2nd edition. p 728-32/Dunnwald LK, et al. Breast Cancer Res. 2007;9(1):R6/Leong A S-Y, et al. Manual of diagnostic immunohistochemistry, 2nd edition. p 375-76