Mouse anti-PTEN , clone 6H2.1 (Monoclonal)

Clone Number: 6H2.1

Immunogen: C-terminal 100 aa of PTEN

Concentration: lot specific

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers. Positive control tissue Breast, Renal Cell and Prostate carcinomas

References: Bose et al. Hum Path 2002;33(4):405-409/Bose et al. Mod Pathol 2006;19(2):238-245

• SKU: SANMON9985
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9985
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG2a
• Host: Mouse
• Conjugate: Unconjugated