Mouse anti-SHP2, clone SIT-01 (Monoclonal)

Clone Number: SIT-01

Immunogen: Bacterially produced recombinant intracellular fragment of human SIT.

Concentration: 1 mg/ml

Storage buffer: Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Additional info: SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.

• SKU: SANMON4021
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON4021
• Green Labware: No
• Package Unit: 0,1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry
• Isotype: IgG1
• Host: Mouse