Mouse anti-Tryptase, clone G3

Clone Number: G3

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Tryptases compose a subfamily of proteinases with trypsin-like activity that are mostly stored in mast cell secretory granules and released into the extracellular environment upon mast cell activation. Several biological functions for tryptases have been proposed, including involvement in inflammatory and allergic responses.1 Mature mast cells have a complex distribution throughout the body. Antitryptase is a useful marker for mast cells.

References: Jordan JH et al. Hum Pathol. 2001 May;32(5):545-52/Gordon LK et al. Clin Immunol. 2000 Jan;94(1):42-50/Ghott A et al. Am J Surg Pathol. 2003 Jul;27(7):1013-9

• SKU: SANMON-RTU1202
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON-RTU1202
• Green Labware: No
• Package Unit: 7 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse