Mouse anti-Tyrosinase, clone T311 (monoclonal)

Clone Number: T311

Immunogen: Recombinant prokaryotic protein corresponding to the tyrosinase molecule.

Concentration: Greater than or equal to 89 mg/L

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: The biosynthesis of melanin in melanocytes involves a family of enzymes, a key member of which is tyrosinase. Tyrosinase deficiency is associated with various forms of albinism and in particular oculocutaneous albinism. L-tyrosinase is the initial substrate for melanin biosynthesis and its conversion to dopaquinone is catalyzed by tyrosinase, whose expression is reported in melanocytes and melanomas.

References: Shidham VB et al. BMC Cancer. 2003; 3(1):15/Lohmann CM et al. American Journal of Surgical Pathology. 2002; 26(10):1351–1357/Clarkson KS et al. Journal of Clinical Pathology. 2001; 54(3):196–200

• SKU: SANMONX10591
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MONX10591
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG2a
• Host: Mouse
• Conjugate: Unconjugated