Mouse anti-Uroplakin III, clone AU-1

Clone Number: AU-1

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, forming complexes of 16nm crystalline particles. UPIII is specific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors.

References: Moll R, et al. Am J Pathol. 1995; 147:1383-97/Olsburgh J, et al. J Pathol. 2003; 199:41-9/Parker DC, et al. Am J Surg Pathol. 2003; 27:1-10

• SKU: SANMON-RTU1207
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON-RTU1207
• Package Unit: 7 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated