Clone Number: CWWB1
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Villin is an actin-binding glycoprotein that serves an important role in the maintenance of the microvilli brush border in gastrointestinal (GI) mucosal epithelium and its associated tumors. Recent immunohistochemical studies with villin have shown that villin is not only expressed in carcinomas of the gastrointestinal tract, but also in renal cell carcinomas, pancreatic carcinomas, endometrial carcinomas, as well as carcinomas of the ovary and lungs. In addition, positive villin expression may be seen in neuroendocrine/carcinoid tumors of the GI tract and lungs.
References: Robert W. Werling et al. Am J Surg. Path.2003; 27(3):303-310/Tamboli P. et al Arch Pathol Lab Med 2002;126:1057-1063/Zhang P. J. et al. Arch Pathol Lab Med. 1999;123:812-816
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