N-Boc-cis-4-Hydroxy-D-proline, CAS 135042-12-5

Product Description: N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.

Applications: Cancer-programmed cell death

Formula: C10H17NO5

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 135042-12-5

Molecular Weight: 231.25

Compound Purity: 99.96

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W002887-25G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W002887-25G
• Package Unit: 25 g
• Quantity Unit: STK