Product Type: Inducer
CAS No.: 119567-63-4
MolecularFormula: C20H41NO2
Molecular Weight: 327,6
Source: Synthetic
Purity: >98%
Solubility: Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
Appearance: White to off-white waxy solid, or viscous oil
PubChem CID: 6438166
Scientific Background: N,N-dimethylsphingosine is a potent and specific inhibitor of sphingosine kinase. It is a natural metabolite of sphiongosine in some cancel cell lines and tissues (1). It also induces apoptosis, but it is not an inhibitor of protein kinase C (2).
References: 1. Yatomi Y., et al. (1996) Biochem. 35: 626-633.2. Sweeny E.A., et al. (1996) Int J Cancer. 66(3): 358-366.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.