N-Succinimidyl 3-(Bromoacetamido)propionate, CAS 57159-62-3

Product Description: N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Applications: Cancer-programmed cell death

Formula: C9H11BrN2O5

References: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 57159-62-3

Molecular Weight: 307.10

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-141385-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-141385-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK