Formulation: A solid
Formal Name: 2-(acetylthio)-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester
Purity: ≥90%
Formula Markup: C8H9NO5S
Formula Weight: 231,2
Shelf life (days): 1460
CAS Number: 76931-93-6
Notes: N-Succinimidyl-S-acetylthioacetate is a protein-modifying agent.{69155} It introduces sulfhydryl groups to proteins via S-acetylthioacetylation of free amine groups, which can be subsequently deprotected by deacetylation to reveal an unprotected thiol. N-Succinimidyl-S-acetylthioacetate has been used in conjunction with the protein cross-linking reagent SMCC (Item No. 28955) in the conjugation of proteins with IgG antibodies for use in ELISAs.{69155,69156}