N4-Acetylcytidine, CAS 3768-18-1

Formulation: A solid

Formal Name: N-acetyl-cytidine

Purity: ≥98%

Formula Markup: C11H15N3O6

Formula Weight: 285,3

Shelf life (days): 1460

CAS Number: 3768-18-1

Notes: N4-Acetylcytidine is a catabolite of cytidine.{65290} It activates BV-2 microglia when used at a concentration of 0.3 mM, an effect that can be blocked by the adenosine A2A receptor antagonist SCH 58261 (Item No. 19676).{65291} It also increases protein levels of the NOD-like receptor protein 3 (NLRP3) inflammasome, an effect that can be blocked by high mobility group box 1 (HMGB1) siRNA in BV-2 microglia. Urine levels of N4-acetylcytidine are increased in mice with tumors induced by 3-methylcholanthrene.{65290} N4-Acetylcytidine is also found as a post-transcriptional modification in RNA.{65292}

• SKU: CAY35219-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35219-10
• Green Labware: No
• Package Unit: 10 g
• Quantity Unit: STK
• Application: Reinstoffe