Native nucleosome (HEK293-derived)

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Applications: Substrate for histone methyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases for drug discovery and HTS applications.

Description: Nucleosomes prepared frommammalian HEK293 cells as a substrate forhistone methyltransferase assay.

Format: Aqueous buffer solution

Formulation: 10 mM Tris-HCl, pH 7.2, 5mM NaCl, 1 mM MgCl2, 0.5 mM CaCl2, 125mM EDTA, and 10 mM Sodium Butyrate

Host Cell Line: HEK293

Storage Stability: At least 6 months at -80°C.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Meagher, R.B., Mussar, K.J., Epigenetics Chromatin 2012 Jul 20;5(1):11.
2. Huang, H., et al., Biosystems 2012 Aug;109(2):214-9.

• SKU: BPS52015
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 52015
• Green Labware: No
• Package Unit: 0.6 mg
• Quantity Unit: STK
• Host: Human