Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II.Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCAPH2
Key Reference: Ono,T., (2003) Cell 115 (1), 109-121
Molecular Weight: 68kDa
Peptide Sequence: Synthetic peptide located within the following region:
SGVPQEAENEFLSLDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Condensin-2 complex subunit H2
Protein Size: 605
Purification: Affinity Purified
Subunit: H2
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