Necrostatin-34, CAS 375835-43-1

Product Description: Necrostatin-34 (Nec-34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain[1].

Applications: COVID-19-immunoregulation

Formula: C18H16N4O2S2

References: [1]Huyan Meng, et al. Discovery of a cooperative mode of inhibiting RIPK1 kinase. Cell Discov. 2021 Jun 1;7(1):41.

CAS Number: 375835-43-1

Molecular Weight: 384.48

Compound Purity: 98.90

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: RIP kinase

• SKU: MEXHY-132203-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-132203-50
• Package Unit: 50 mg
• Quantity Unit: STK