Target: Neuroligin 4
Conjugate: RPE
Product Type: Monoclonal
Clone Number: N98/7 (Formerly sold as S98-7)
Immunogen: Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.
Swiss-Prot: B0F2B4
Purification: Protein G Purified
Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Concentration: 1 mg/ml
Specificity: Detects ~125-130kDa. Does not cross-react with other Neuroligins.
Cellular Localization: Cell Membrane,Cell Junction
Scientific Background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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