NGB 2904, CAS 189060-98-8

Description: NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).

CAS Number: 189060-98-8

Formula: C28H29Cl2N3O

Molecular Weight: 494,46

References: Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18.

• SKU: TGMT28167-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T28167-1mL
• Package Unit: 1 mL
• Quantity Unit: STK