NGI-1, CAS 790702-57-7

Product Description: NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B[1]. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability[2].

Applications: Cancer-programmed cell death

Formula: C17H22N4O3S2

References: [1]Zhu S, et al. Comprehensive Interactome Analysis Reveals that STT3B is Required for the N-Glycosylation of Lassa Virus Glycoprotein. J Virol. 2019 Sep 11. pii: JVI.01443-19./[2]Lopez-Sambrooks C, et al. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol. 2016 Dec;12(12):1023-1030.

CAS Number: 790702-57-7

Molecular Weight: 394.51

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : 7.14 mg/mL (ultrasonic)

Target: Virus Protease

• SKU: MEXHY-117383-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-117383-50
• Package Unit: 50 mg
• Quantity Unit: STK