Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: NHLH1 may serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NHLH1
Key Reference: Manetopoulos,C., (2003) Biochem. Biophys. Res. Commun. 307 (4), 891-899
Molecular Weight: 14kDa
Peptide Sequence: Synthetic peptide located within the following region:
AKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Helix-loop-helix protein 1
Protein Size: 133
Purification: Affinity Purified
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