Nigericin, CAS 28643-80-3

NALP3 activator

Product Type: Inducer

CAS No.: 28643-80-3

MolecularFormula: C40H67NaO11

Molecular Weight: 746,94

Source: Synthetic

Purity: >98%

Solubility: Soluble to 50 mM in DMSO and 20 mM in ethanol

Appearance: White to off-white Solid

PubChem CID: 23681158

Scientific Background: Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.

References: 1. Vercesi A.E., et al. (1993) J Biol Chem. 268: 8564.2. Graven S.N., Estrada-O, S., Lardy H.A. (1966) Proc Natl Acad Sci USA. 56(2): 654-658.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-229-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-229-50MG
• Package Unit: 50 mg
• Quantity Unit: STK