Clone Name: ZR176
Application Note: IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 39
Positive Control: Normal thyroid or lung
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Uniprot ID: P43699
Antigen Species: Human
Immunogen: Recombinant human TTF-1 protein
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: NK2 homeobox 1
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