Product Type: Redox Probe
MolecularFormula: C23H21N5O4
Molecular Weight: 431,45
Source: Synthetic
Solubility: Soluble in DMSO
Appearance: Red Solid
Scientific Background: NpFR1, or napthalimide-flavin redox sensor 1, is a novel flavin molecule that exhibits a greater than 100-fold increase in fluorescence upon oxidation, and is easily reversible. In the oxidative form, is shows a maximum absorption at 395 and 463nm, max admission at 545nm. Treatment with a mild reducing agent (including sodium thiosulfate, sodium cyanoborohydride, DTT and glutathione) gave the reduced form which exhibited 110-fold lower absorbance, and 125-fold lower emission. Re-oxidation to its original fluorescence can be achieved by air or by hydrogen peroxide.
References: 1. Yeow J., Kaur A.K., Anscomb M.D., and New E.J. (2014) Chem. Commun. 50: 8181-8184.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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