NRAS Polyclonal Antibody, Rabbit

Abbreviation: NRAS

Target Synonym: NRAS;ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6

Conjugation: Unconjugated

UNIProt ID: P01111

Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human NRAS

Dilution: WB 1:500-1:2000,IF 1:50-1:200

• SKU: ELSE-AB-92783-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92783-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Western Blotting
• Isotype: IgG
• Host: Rabbit