NSC-66811, CAS 6964-62-1

p53/mdm2 inhibitor

Product Type: Inhibitor

CAS No.: 6964-62-1

MolecularFormula: C23H20N2O

Molecular Weight: 340,4

Source: Synthetic

Purity: >98%

Solubility: Soluble in 25 mg/ml DMSO

Appearance: White Solid

PubChem CID: 248986

Scientific Background: A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.

References: 1. Lu Y., et al. (2006) J. Med.Chem. 49: 3759.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-338-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-338-50MG
• Package Unit: 50 mg
• Quantity Unit: STK