Nutlin-3, CAS 548472-68-0

p53/mdm2 inhibitor

Product Type: Inhibitor

CAS No.: 548472-68-0

MolecularFormula: C30H30Cl2N4O4

Molecular Weight: 581,9

Source: Synthetic

Purity: >98%

Solubility: Soluble in 100 mM DMSO and Ethanol

Appearance: Yellow solid

PubChem CID: 216345

Scientific Background: MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 µM) and activates p53. Antiproliferative agent; induces apoptosis in cancer cells.

References: 1. Vassilev et al (2004) Science 303: 844.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-344-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-344-5MG
• Package Unit: 5 mg
• Quantity Unit: STK