Clone Name: HL2072
Light Chain: Kappa
Application Note: WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 116
Specificity/Sensitivity: This antibody is specific for human OGDH protein, and it does not cross react with human OGDHL protein.
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
Uniprot ID: Q02218
Antigen Species: Human
Immunogen: Recombinant fragment of human OGDH.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: oxoglutarate dehydrogenase
English
Deutsch
