Olaparib, CAS 763113-22-0

Description: Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

CAS Number: 763113-22-0

Formula: C24H23FN4O3

Molecular Weight: 434,46

References: Prasad CB, et al. Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits anti-metastatic property. Sci Rep. 2017 Oct 9;7(1):12876.

• SKU: TGMT3015-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T3015-5mg
• Package Unit: 5 mg
• Quantity Unit: STK