Application Note: WB: 1:2000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 11
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium Azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Uniprot ID: P02818
Antigen Species: Human
Immunogen: A KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human Osteocalcin.
Purification: Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation: Unconjugated
Full Name: bone gamma-carboxyglutamate protein
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