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Encompassing Amino Acids: 20-211
Application: Useful for studying protein binding interactions and screening inhibitors.
Description: Mouse OX40, also known as Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, and CD134, GenBank Accession No. NM_011659, a.a. 20-211 with C-terminal Avi-Tag fused to the Fc portion of Human IgG1 and expressed in a HEK293 cell expression system. This protein is enzymatically biotinylated using Avi-Tag™ technology. This protein runs at a higher MW by SDS-PAGE due to glycosylation. MW = 52 kDa.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_011659
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: P33681
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Linton, P.J., et al., J. Exp. Med. 2003; 197(7): 875-883.2. Arestides, R.S.S., et al., Eur. J. Immunol. 2002; 32(10): 2874-2880.
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