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Encompassing Amino Acids: 1046-1163
Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Description: Human bromodomain E1A binding protein p300, also known as EP300, KAT3B, or RSTS2, GenBank Accession No. NM_001429, a.a. 1046-1163 corresponding to single bromodomain with N-terminal His-tag, MW=15.1 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_001429
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: Q09472
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Gui, Y., et al., Nat. Genet. 2011 Aug 7;43(9) : 875 - 878.
2. Morin, R.D., et al., Nature. 2011 Jul 27;476(7360) : 298 - 303.
3. Zhao, Z., et al., Brain Res. Bull. 2011Oct 10; 86(3-4) : 189 - 194.
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