p53 antibody

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 42

Positive Control: 3dpf zebrafish embryos treated with UVC

Form: Liquid

Buffer (with preservative): PBS, 20% Glycerol, 0.025% ProClin 300.

Concentration: 1.47 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.

Uniprot ID: P79734

Antigen Species: Zebrafish

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of zebrafish p53. The exact sequence is proprietary.

Purification: Purified by antigen-affinity chromatography.

Conjugation: Unconjugated

Full Name: tumor protein p53

• SKU: GTX128135-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX128135-100
• Green Labware: No
• Package Unit: 100 μl
• Quantity Unit: STK
• Reactivity: Zebrafish
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Human Gene ID: 30590
• Host: Rabbit