Abbreviation: p70 S6 Kinase 1
Target Synonym: PS6K;S6K;S6K-beta-1;S6K1;STK14A;p70 S6KA;p70(S6K)-alpha;p70-S6K;p70-alpha;P70 S6K;RPS6KB1;p70S6KA
Conjugation: Unconjugated
UNIProt ID: P23443
Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human P70 S6K
Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200
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