Product Description: Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively)[1].
Applications: Cancer-programmed cell death
Formula: C65H83NO17
References: [1]University of California, et al. Modified small molecule cytotoxins and albumin or mimetics for use in treatment of cancer. United States, US20170080094 A1 2017-03-23
CAS Number: 2089211-45-8
Molecular Weight: 1150.35
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Others