Clone Name: GT1259
Application Note: WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 58
Form: Liquid
Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Concentration: 0.53 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13177
Antigen Species: Human
Immunogen: A synthesized peptide derived from human PAK2
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: p21 (RAC1) activated kinase 2
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