Formulation: A solution in water
Formal Name: N1,N24-bis(2-aminoethyl)-4,21-bis[3-[(2-aminoethyl)amino]-3-oxopropyl]-11,14-bis[3-[[2-[bis[3-[(2-aminoethyl)amino]-3-oxopropyl]amino]ethyl]amino]-3-oxopropyl]-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanediamide
Formula Markup: C62H128N26O12
Formula Weight: 1429,9
Shelf life (days): 730
CAS Number: 142986-44-5
Notes: PAMAM dendrimer G1.0 amine (PAMAM G1.0) is a polyamidoamine (PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro.{49819} It is approximately 22 Å in diameter and has 8 surface groups.{51536} Micelles composed of PAMAM G1.0 conjugated to di-n-dodecylamine and encapsulating 5-fluorouracil (5-FU; Item No. 14416) increase the solubility of 5-FU and are cytotoxic to AGS gastric adenocarcinoma cells.{49819} PAMAM G1.0 conjugated to the clay mineral palygorskite (Pal-G1.0) on a PVDF membrane adsorbs the heavy metals nickel(II), cadmium(II), and copper(II) from aqueous solutions.{49820}
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