PAMAM Dendrimer G3.0 Succinamic Acid (water solution)

Formulation: A solution in water

Formula Weight: 10109

Shelf life (days): 730

Notes: PAMAM dendrimer G3.0 succinamic acid (PAMAM G3.0 succinamic acid) is a polyamidoamine (PAMAM) dendrimer with succinamic acid termini that has been used as a drug delivery system in vivo.{72167} It is approximately 35 Å in diameter in PBS and has 32 surface groups.{67576,67552} PAMAM G3.0 succinamic acid (10 µM) inhibits plaque formation induced by Middle East respiratory syndrome coronavirus (MERS-CoV) in infected Vero cells.{67552} It is active against S. aureus.{51558} Intravenous administration of PAMAM G3.0 succinamic acid conjugated to the tubulin polymerization inhibitor combretastatin A4 (combrestatin A4; Item No. 10007412) increases intratumoral necrosis and decreases intratumoral blood flow in an orthotopic U251 glioma rat xenograft model.{72167}

• SKU: CAY39120-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39120-500
• Package Unit: 500 mg
• Quantity Unit: STK