Clone Name: HL2599
Light Chain: Kappa
Application Note: WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 47
Specificity/Sensitivity: This antibody is specific for human PAX6 protein, and it does not cross react with human PAX2, PAX4, PAX5, and PAX8 protein.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
Uniprot ID: P26367
Antigen Species: Human
Immunogen: Recombinant fragment of Human PAX6.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: paired box 6
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