PBD-monoamide, CAS 2093165-00-3

Product Description: PBD-monoamide, a modified PBD (pyrrolobenzodiazepine) dimer, is an ADC Cytotoxin. PBD-monoamide can be used for synthesis of DHES0815A (an HER2 ADC). PBD-monoamide has DNA-binding activity and reduces cell viability[1].

Applications: Cancer-programmed cell death

Formula: C33H36N4O7

References: [1]Lewis GD, et al. The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results. Nat Commun. 2024 Jan 11;15(1):466.

CAS Number: 2093165-00-3

Molecular Weight: 600.66

Research Area: Cancer

Solubility: DMSO : 150 mg/mL (ultrasonic)

Target: ADC Cytotoxin

• SKU: MEXHY-161252-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161252-0
• Package Unit: Get quote
• Quantity Unit: STK